Description

Actovegin dragees 60x

Pharmacological Effects:

Actovegin by increasing the transport and accumulation of glucose and oxygen, increasing their intracellular disposal. These processes result in the acceleration of the metabolism of ATP (adenosine triphosphate), and increase energy cells. under conditions that limit the normal functions of energy metabolism (hypoxia / deficient oxygen supply or violation of its assimilation / lack of substrate) and with increased consumption of energy (healing, regeneration / tissue repair /), Actovegin stimulate energetic processes of the useful metabolism (the method of metabolism in body) and anabolism (the process of assimilation of drugs by the body). Secondary result is to increase blood flow.

Indications:

Cerebrovascular insufficiency, ischaemic stroke (insufficient supply of brain tissue oxygen because of acute ischaemic attacks), head injuries, disorders of peripheral circulation (arterial, venous); angiopathy (disturbance of vascular tone), trophic disorders (eating disorders of skin) for unhealthy varicose veins of the legs (venous changes, characterised by an uneven increase in their lumen with the formation of a diverticulum wall because of disfunction of valvular), ulcers of various origin, bedsores (necrosis of tissue caused by prolonged pressure on them by lying down), burn hindrance and treatment of radiation injuries .

Damage to the cornea (the clear covering the eye) and sclera (opacity of the eye): the burn of the cornea (acids, alkalis, lime), corneal ulcers of various origin, keratitis (inflammation of the cornea), together with post-transplant (transplant), corneal abrasions of the cornea in patients contact lenses; prevention of defeats within the choice of contact lenses in patients with degenerative processes within the cornea (for use eye gel), also on accelerate the healing of venous ulcers (slow-healing skin defects), bedsores (necrosis of tissue caused by prolonged pressure on them by lying ), burns, radiation skin lesions, etc.

How to use:

Dose and route of administration depend upon the kind and severity of sickness. The drug was appointed interior, parenterally (bypassing the digestive tract) and topically.

Inside the dose is 1-2 pills three times daily before meals.

For intravenous or intraarterial administration, depending on the severity of the sickness starting dose is 10-20 milliliter. Then designate five milliliter by slow intravenous or injection, one time on a daily basis every day or many times per week. Intravenously injected 250 milliliter solution for infusion at a rate of 2-3 milliliter per minute, a once daily or many times per week. you’ll also use ten, twenty or fifty milliliter solution for injection, diluted in 200-300 milliliter of glucose or saline. Total per course of treatment – 10-20 injections. within the infusion solution isn’t suggested to feature other medicine.

Parenteral actovegin should be undertaken with caution due to the chance of an anaphylactic (allergic) reaction. suggested test administration, and also the need to give facilities for emergency treatment. Intravenously will be administered no more than five milliliter as hypertonic solution has the properties (osmotic pressure of the solution is more than the osmotic pressure of blood). With intravenous drug use is suggested to watch the performance of water-electrolyte metabolism.

Local application. Gel is indicated for the purification and treatment of open wounds and ulcers. Gels can be applied directly on the skin for burns or any kind of radiation injuries. within the treatment of ulcers of the gel applied to the skin over a thick layer and cover wrap with ointment actovegin to stop sticking to the wound. Dressing changes produce a once a week, with abundant weeping sores – many times each day.

Cream is used to enhance wound healing, and weeping wounds. Use once the formation of pressure ulcers and bar of radiation injuries.

The ointment is applied with a thin layer on the skin. Apply for the long-term treatment of wounds and ulcers so as to accelerate their epitelizaiii (healing) once treatment with gel or cream. To prevent pressure sores ointment should be applied to relevant areas of the skin. For the prevention of radiation skin lesions ointment should be applied after exposure or within the intervals between sessions.

Side effects:

Allergic reactions: hives, feeling a rush of blood, sweating, increased blood heat. Itching, burning within the application of a gel, ointment or cream, the applying of eye gel, lachrymation, scleral injection (redness of the sclera).

Contraindications:

Hypersensitivity to the drug. With care the drug throughout pregnancy. throughout the period of breast-feeding use actovegin undesirable.

Product:

Dragees forte during a package of one hundred items. solution for injection ampoules PA2, five and ten milliliter (1 milliliter – forty mg). solution for infusion 100 percent and two hundredth with saline in vials of 250 milliliter. 200th gel in tubes of 1920 five-hitter cream in tubes of 1920 five-hitter Ointment in tubes of 1920 Eye Gel two hundredth in tubes of five g.

Storage Conditions:

In a dry place at temperatures no over eight * C.