Description

Get nm-2201 on-line, NM-2201 is an artificial cannabinoid that’s presumably a full agonist and unselectively binds to CB1 and CB2 receptors with low nanomolar affinity. very little to no research information available on this chemical makes it not possible to explain it’s properties very well.

However, it’s an analogue of another artificial cannabinoid AM-2201, which means it would share some similarities. This was a drug which was discovered by Alexandros Makriyannis from Northeastern University. it’s been told by users that this drug is that the most potent chemical from these sorts of medicine. The physiological and toxicological properties of this compound haven’t been evaluated. This product is meant for forensic and analysis applications.

Its official designation within the IUPAC system is defined naphthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate , and easy formula of the substance is summed up as C24H22FNO2 , with the molecular weight determined to be 375.4 g/mol.

Solvents as ethyl alcohol,DMSO, dichloromethane and dimethylformamide purged with a inert gas.NM-2201 is sparingly soluble in liquid solutions.To enhance liquid solubilty, dilute the organic solvent answer into liquid buffers or isotonic saline.If playing biological experiments,ensure the residual quantity of organic solvent is insignificant, since organic solvents could have physiological effects on low concentrations. . it’s not suggested storing the solution for over one day.

This drug is, however, used as a narcotic and people who have used it testify that this is often one among the most effective cannabinoids once it comes to euphoric experiences. The drug is often sprayed on botanic material and smoked, though it may be eaten in liquid or powder form.
To learn the characteristics of NM-2011 one will check with the characteristics of AM-2201. AM-2201 could be a drug whose chemical properties are studied. However, specific toxicity and chemical properties of NM-2201 aren’t offered.

Users of this drug have testified that there are little side effects to the drug; there’s no nausea or panic attacks once coming down or throughout the peak. The drug includes a fast and powerful result. It may be burnt and smoked. there’s a control of delicate disassociation with its use. the results won’t last that a lot of however it’s potent.

The powder of NM-2201 can quickly burn under fire; users then smoke the contents. This artificial cannabinoid is typically taken in doses of five mg or a bit over ten mg. This amount needed could be a heap but different artificial cannabinoids, that poses a problem of terribly frequent dose. the same old quantity used is around a pair of mg. The drug acts as an agonist to the central cannabinoid (CB1) and therefore the peripheral cannabinoid (CB2) receptors.

Effects caused by this drug once usage embody panic and anxiety attacks. With terribly little doses, as little as 2mg, some individuals may expertise nausea. There are reports of convulsions being caused by doses of ten mg. This drug is thus potent that a sample as little as 500µg is completely active. Once the drug is manufactured, it will stay stable for about one year.

This item was created completely for analysis functions. However, many folks have used it for recreational functions. there’s little documentation regarding the experiences of users and therefore the aftermath, if any.

this is often the most effective cannabiniod since JWH-018, and I’ve tried plenty of different synthetics out there since the ban. Comes on fast and powerful and even causes a small amount of mild disassociation sort of a weak dose of MXE. appears to be a powerful, if not full, agonist at each CB1 and CB2 cannabinoid receptors. it would not last quite as long as JWH-018 however it definitely is potent. My ROA is mistreatment the tip of an Exacto blade to dump an eyeballed quantity on high of a bit of red hot hooka charcoal and inhaling the smoke using a glass tube. This leads to a fast and complete burn. I’ve been exploitation hooka charcoal since the late 70’s after I first used it for smoking Jamaican hash oil. It may be used for any RC, or any drug for that matter, that needs smoking.”
NM-2201 is illegal in Sweden and germany.

Chemical information of NM-2201

Molar Refractivity: 109.0±0.5 cm3
#H bond acceptors: three
#H bond donors: zero
#Freely Rotating Bonds: eight
#Rule of five Violations: one
ACD/LogP: half dozen.49
ACD/LogD (pH five.5): 5.75
ACD/BCF (pH five.5): 13832.67
ACD/KOC (pH five.5): 32036.73
ACD/LogD (pH seven.4): 5.75
ACD/BCF (pH seven.4): 13832.67
ACD/KOC (pH seven.4): 32036.73
Polar Surface Area: thirty one Å2
Polarizability: forty three.2±0.5 10-24cm3
Surface Tension: forty two.2±7.0 dyne/cm
Molar Volume: 322.2±7.0 cm3
Smiles: FCCCCCN1C=C(C(=O)OC2=CC=CC3=CC=CC=C23)C2=CC=CC=C12

InChI: 1S/C24H22FNO2/c25-15-6-1-7-16-26-17-21(20-12-4-5-13-22(20)26)24(27)28-23-14-8-10-18-9-2-3-11-19(18)23/h2-5,8-14,17H,1,6-7,15-16H2

InChI key: PRGFSQYZCKCBQO-UHFFFAOYSA-N

Formula: C24H22FNO2
Isotope formula: C24H22FNO2
Composition: C (76.78%), H (5.91%), F (5.06%), N (3.73%), O (8.52%)
Isotope composition: C (76.78%), H (5.91%), F (5.06%), N (3.73%), O (8.52%)
Mass: 375.4354
Exact mass: 375.163457158